List of DC Comics characters: S

- superman - Superboy - Supergirl

S

 * S.T.R.I.P.E. (also known as Stripesy and Pat Dugan)
 * S'lyton, Lord (WildStorm)
 * S'vor
 * Saaba
 * Sa'ar, the Ageless One
 * Saarek
 * Saba-1
 * Sabbac (I) & (II)
 * Saber-Tooth (also known as Ross Malverk)
 * Saber-Tooth (also known as Loretta Nordan)
 * Sabina
 * Sable Thorpe (Warner Bros. Animation (DCAU))
 * Sabre
 * Sabrina (Warner Bros. Television)
 * Sacker
 * Sacks, Evan
 * Sadie Falk (also known as Jayne Payton)
 * Safir, Nadia
 * Sage, Vic (also known as Question)
 * Sagebrush (also known as Cal)
 * Sagebrush Sam
 * Sagittarius (also known as Lazlo Trask)
 * Said, David (also known as King (IV))
 * Sailor
 * Sailor Sorenson
 * Saint (also known as Remi Rome) (Vertigo)
 * Saint Columba
 * Saint Germain, Pol
 * Saint Lucifer, Gaston
 * Saint Walker
 * Saki, Captain
 * Sakki (also known as Tokai)
 * Sakko Warner (Warner Bros. Animation)
 * Sal
 * Sala Nisaba (also known as Ishtar)
 * Salaak (also known as Green Lantern of Space Sector 1418)
 * Salak
 * Salamanca
 * Salamandroid
 * Salima Baranizar
 * Sallucci, Caz
 * Sally King
 * Sally Norris
 * Sally Saunders
 * Sally Sonic (also known as Sally Smart)
 * Salty Sam
 * Saltz, Cheryl (Milestone Media)
 * Salu Digby (also known as Shrinking Violet, Violet and Atom Gitl)
 * Salavtore Valestra (Warner Bros. Animation (DCAU))
 * Salvo Smith (Warner Bros. Animation (DCAU))
 * Sam
 * Sam (Fawcett Comics)
 * Sam Dales
 * Sam Foswell (also known as Fosgoyle)
 * Sam Giddell (Warner Bros. Animation (DCAU))
 * Sam Guthrie (also known as Torpedo) (Amalgam Comics)
 * Sam Kurtis
 * Sam Lane
 * Sam Makoa (Amalgam Comics)
 * Sam Pryor (Warner Bros. Animation (DCAU))
 * Sam Schwartz (Tangent Comics)
 * Sam Simeon
 * Sam Spulby
 * Sam Valentine
 * Sam Young (Warner Bros. Animation (DCAU))
 * Samantha
 * Samantha Crockett
 * Samantha Morgan
 * Samari, Nasreen (also known as Persian)
 * Samarithan Hook
 * Samarkand Greenblatt
 * Samira
 * Samosa
 * Samoth, Tros (also known as Raven and Shadowlord)
 * Samsara
 * Samsarra, Ahmed (also known as White King (I))
 * Samson
 * Samson Citadel
 * Samuel J. Scudder (also known as Mirror Master)
 * Samuel Newton
 * Samuel Newton's housekeeper
 * Samuel Rayburn
 * Samuel Register (also known as Zookeeper)
 * Samuel Solomon
 * Samuel Sullivan (also known as "Made of Wood" Killer (I))
 * Samuel Tanner
 * Samuels, Assistant District Attorney
 * Samuels, Carol
 * Samurai (I)
 * Samurai (II)
 * Sanborne, Kelly (Milestone Media)
 * Sanchez
 * Sanchez (Warner Bros. Animation (DCAU))
 * Sanchez, Isobel
 * Sanchez, Jorge
 * Sanchez, Manuel
 * Sanchez, Mister
 * Sand Demon
 * Sanders Hotchkins
 * Sanderson (Amalgam Comics)
 * Sanderson, Robert (Vertigo)
 * Sandman (alias Daniel Hall)
 * Sandman (alias Dream, Morpheus)
 * Sandman (alias Garrett Sanford)
 * Sandman (also known as Hector Hall and Doctor Fate)
 * Sandman (also known as Wesley Dodds)
 * Sandman (20th Century-Fox Television)
 * Sandman Superman
 * Sandoval, Guillermo (also known as Runt) (WildStorm)
 * Sandra
 * Sandra McClane
 * Sandra "the Bear" Barrett
 * Sandra, Princess (20th Century-Fox Television)
 * Sandro Batorn
 * Sands, Carl (also known as Shadow Thief (I))
 * Sandsmark, Cassie (also known as Wonder Girl)
 * Sandstorm
 * Sandy Kean
 * Sandy Powers
 * Sandy Saturn
 * Sandy Hawkins (also known as Sandy the Golden Boy, Sand and Sandman)
 * Santa Claus (Vertigo)
 * Santorelli, Peter
 * Saoud
 * Sapling
 * Sappal, Airam
 * Sappal, Nhoj
 * Sapphire
 * Sapphire Stagg
 * Sapphire, Lady
 * Saraar
 * Sarah (Warner Bros. Animation (DCAU))
 * Sarah Charles
 * Sarah Essen Gordon
 * Sarah Lang
 * Sarah Olsen
 * Sara Quinones (also known as Flashback) (Milestone Media)
 * Sarah Rainmaker (also known as Rainmaker) (WildStorm)
 * Sarasim (Warner Bros. Animation)
 * Sardath
 * Sardine
 * Sardine
 * Sardonyx, Lord
 * Sarge (also known as Sarge Clay)
 * Sarge
 * Sarge (DC Comics/Dark Horse Comics)
 * Sarge Steel (also known as King (II))
 * Sargon the Sorcerer (also known as John Sargent)
 * Sarko
 * Sarkus
 * Sarn, Vath
 * Sarr-Penn
 * Sarwan
 * Sasha (Vertigo)
 * Sasha Bordeaux (also known as Black Queen (II))
 * Sasha Green (also known as Myriad)
 * Sasha Lo (Peacock)
 * Sasha Woodman (Warner Bros. Television)
 * Sashina
 * Satan (an alias of Rol-Nac)
 * Satan (DC Comics/''Dark Horse Comics')
 * Satan Girl
 * Satana, the Tiger Girl (also known as Sara Descarl)
 * Satanis, Lord
 * Satanus, Lord
 * Sataroth
 * Satin Satan (also known as Sabrina Sultress)
 * Sato, Takeo (also known as Sunburst)
 * Saturn
 * Saturn Girl
 * Saturn Lad (an alias of Sun Boy)
 * Saturn Queen
 * Saturna
 * Saturno, Mephisto
 * Satyr (Fawcett Comics)
 * Satyricus
 * Saul Erdel (also known as Mark Erdel and James Erdel)
 * Saunders (Warner Bros. Animation (DCAU))
 * Saunders, Greg (also known as Vigilante and Greg Sanders)
 * Saunders, Joshua (also known as Takion)
 * Sanders, Lieutenant
 * Saunders, Matt
 * Saunders, Mitchell (also known as Cannon) (WildStorm)
 * Saunders, Will (also known as Whistler Will)
 * Savage Skull (also known as Jack Crane)
 * Savage, Black Tom (Amalgam Comics)
 * Savage, King
 * Savage, Pete (20th Century-Fox Television)
 * Savage, Vandal
 * Savant
 * Savant (also known as Kenesha) (WildStorm)
 * Savenlovich, Anya
 * Savior
 * Saviour
 * Savitar
 * Sawyer, Maggie
 * Sax Carlin
 * Sax Girl
 * Sayar, Professor
 * Sayd
 * Sayre, Waverly
 * Sayyar
 * Sazu
 * Scab (Warner Bros. Animation (DCAU))
 * Scalphunter (also known as Brian Savage)
 * Scandal
 * Scanlon, Butch
 * Scanlon, Congressman
 * Scanner
 * Scapegoat, Lord
 * Scar
 * Scar Jameson
 * Scarab (I)
 * Scarab
 * Scarab (Vertigo)
 * Scarabus
 * Scarback
 * Scarebeast (see Scarecrow)
 * Scarecrone
 * Scarecrow
 * Scrarecrow (Amalgam Comics)
 * Scareware
 * Scarface
 * Scarface (Warner Bros. Animation) (DCAU)
 * Scarhart
 * Scarlet
 * Scarlet Cyclone (Hanna-Barbera)
 * Scarlet Harlot (also known as Crazy Jane)
 * Scarlet Scarab (Warner Bros. Animation)
 * Scarlet Scythe
 * Scarlet Skier
 * Scarletti
 * Scarmaglione
 * Scarrba the Protector
 * Scarth
 * Scathe
 * Scavenger (I) & (II)
 * Scavone, Marty
 * Scheer, Ron
 * Schivel, Doctor (an alias of Mister Freeze) (20th Century-Fox Television)
 * Schlagg-Man
 * Schmidlapp, Commodore (20th Century-Fox)
 * Schmidt, Hans
 * Schneider, Fred
 * Schneiderman, Murray "the Swede"
 * Schott, Winslow P. (also known as Toyman)
 * Schreck
 * Schultz, Lulu (also known as Lola Lasagne) (20th Century-Fox Television)
 * Schwartz, Julius
 * Scirocco
 * Scissors
 * Scivor
 * Scoop Scanlon
 * Scoop Smith (Fawcett Comics)
 * Scoopshovel
 * Scooter
 * Scorch
 * Scorcher (I-III)
 * Scorn
 * Scorpia
 * Scorpion
 * Scott Fischer
 * Scott Forest
 * Scott Free (also known as Mister Miracle)
 * Scott Harris
 * Scott Jameson
 * Scott Krauss
 * Scott Sawyer (also known as Warmaker One)
 * Scott Tucker (also known as Thunderhead (II))
 * Scott, Alan (also known as Green Lantern (I), Sentinel and White King (II))
 * Scott, Noah (an alias of the Black Pirate)
 * Scott, Roger
 * Scotty
 * Scourge
 * Scout 627
 * Scrap (Warner Bros. Animation (DCAU))
 * Scrapper (also known as Patrick MacGuire)
 * Scratch, Nicholas
 * Scream Queen
 * Screaming Skull
 * Scribbly
 * Scuffy the Tramp
 * Scuzzy (also known as Curtis P. Howell)
 * Sden
 * Sea Ape
 * Sea Castle police chief (Fawcett Comics)
 * Sea Scamp (Filmation)
 * Sea Sorcerer (Filmation)
 * Sea Sleuth
 * Sea Thief
 * Sea Wolf
 * Seagrin
 * Seaguy
 * Seamus O'Brien (also known as Deathtrap) (WildStorm)
 * Sean Carter
 * Sean Miller (Warner Bros. Animation (DCAU))
 * Sean O'Grady (also known as Hot-Head)
 * Sebastian Beale
 * Sebastian Blood (see Brother Blood (II))
 * Sebastian Faust
 * Sebastian Hady
 * Sebastian Ives
 * Sebastian, Brother (see Brother Blood (I))
 * Sebirus (Gorilla Comics/DC Comics)
 * Second Elder (Warner Bros.)
 * Second Hand
 * Second of the Fallen (Vertigo)
 * Secret
 * Secretary General of the United Nations
 * Security guard (Warner Bros. Animation (DCAU))
 * Sedgwick, Abner (It's a Bird...It's a Plane...It's Superman)
 * Seeker (I-II)
 * See-More (Warner Bros. Animation)
 * Seer
 * Seer Ruggle
 * Seera
 * See-Through-Slasher (also known as Predator) (20th-Century Fox)
 * See-Thru Robber (also known as Lloyd "Eddie" Ventrix) (Warner Bros. Animation (DCAU))
 * Segar, Missus (Warner Bros. Animation (DCAU))
 * Sekhmet
 * Selaya
 * Seldon
 * Selena (Fawcett Comics)
 * Selkirk, Penn
 * Selma Jones (also known as Princess Primrose) (20th Century-Fox Television)
 * Selzheim, Han
 * Seminole Sam (Fawcett Comics))
 * Senator Armstrong
 * Senator Barrows
 * Senator Finch (Warner Bros. Animation (DCAU))
 * Senator Hastings
 * Sendrina
 * Seneca
 * Senior Waveman Kimura (also known as Junior Waveman and Riki Kimura)
 * Senior Waveman Otomo (also known as Senior Waveman Otomo)
 * Senius, Circadia
 * Senorita Navaja
 * Senreich, Mattheus (WildStorm)
 * Sensei
 * Sensei (also known as White Toshi)
 * Sensor (also known as Jeka Wynzorr; rebooted version of Princess Projectra)
 * Sensor
 * Sensor Girl (also known as Princess Projectra)
 * Sentient Sector 3600
 * Seraph
 * Serge Orloff
 * Sergeant Bilko (CBS Television)
 * Sergeant Blake
 * Sergeant Brennan
 * Sergeant Casey
 * Sergeant Cloud
 * Sergeant Dexter
 * Sergeant Dobbs
 * Sergeant Gallagher
 * Sergeant Hallix
 * Sergeant Nichols (also known as Bulldozer (I))
 * Sergeant Pruett
 * Sergeant Rawlings
 * Sergeant Rock (also known as Frank Rock)
 * Sergeant Smith
 * Sergei
 * Serifan
 * Serling, Rod (Vertigo)
 * Serpena
 * Serpenteen
 * Serpetine
 * Servant of Darkness (Lydea Mallor clone)
 * Servant of Darkness (Oan clone)
 * Servant of Darkness (Orion clone)
 * Servant of Darkness (Superman clone)
 * Server Aja
 * Set
 * Setag Retss
 * Setap
 * Seth (Vertigo)
 * Seth Cowie (WildStorm)
 * Seti
 * Sett
 * Sev Tcheru (also known as Evolvo Lad)
 * Sewer King (Warner Bros. Animation (DCAU))
 * Sexton (''Vertigo')
 * Seymour
 * Seymour Grey (Warner Bros. Animation (DCAU))
 * Seymour Wastely
 * Shade
 * Shade (also known as Richard Swift)
 * Shade, the Changing Man
 * Shado
 * Shadow (also known as Kent Allard and Lamont Cranston)(Condé Nast Publications)
 * Shadow Kid (also known as Grev Mallor)
 * Shadow Lass (also known as Tasmia Mallor and Umbra)
 * Shadow Storm
 * Shadow Thief (I & II) (also known as Carl Sands (I) & Hammer (II))
 * Shadowdragon (also known as Savitar Bandu)
 * Shadower
 * Shadowstryke
 * Shaggy Dawg
 * Shaggy Man
 * Shaggynaut (Amalgam Comics)
 * Shagrek
 * Shahn-Zi
 * Shakedown
 * Shakes
 * Shakes
 * Shakespeare, Judith (Vertigo)
 * Shakespeare, Kent
 * Shakespeare, Hamnet (Vertigo)
 * Shakespeare, William (Vertigo)
 * Shakira
 * Shaler, Art
 * Shaligo the Flying Finback
 * Shalox
 * Shame (20th Century-Fox Television)
 * Shamir (Warner Bros. Animation (DCAU))
 * Shamma
 * Shamrock
 * Shands, Michael
 * Shane Thompson (also known as Proselyte)
 * Shango
 * Shank Taylor (also an alias of Batman)
 * Shanna
 * Shanner, Eric
 * Shannon (Warner Bros. Animation (DCAU))
 * Shannon, Pop (Lippert Pictures, Inc.)
 * Shape
 * Shapiro, Joseph (also known as Wildman)
 * Shaqira Johnson (also known as Windsprint) (WildStorm)
 * Sharif (also known as Davood Nassur and Sinbad)
 * Shark I-III (T.S. Smith is an alias of the third Shark)
 * Shark (also known as Gunther Hardwick)
 * Shark Armstrong
 * Shar-La
 * Sharn of Iwo
 * Sharon
 * Sharon Fox (Warner Bros. Animation (DCAU))
 * Sharon Magnus (also known as Platinum (I), Tina Platt and Platina)
 * Sharpe
 * Sharpe, Mark
 * Shathan
 * Shatt, Howard
 * Shatterfist
 * Shatterstarfire (Amalgam Comics)
 * Shaw, Craig
 * Shaw, Missus
 * Shaw, Mordecai (see Monstrosity) (WildStorm)
 * Shayera Hol (also known as Hawkgirl and Hawkwoman)
 * Shazam (Fawcett Comics)
 * She-Bat (also known as Francine Langstrom)
 * She-Cat
 * Sheer Shears (Milestone Media)
 * Sheik Ali Flesh (Vertigo)
 * Sheik Hassan
 * Shelby, David
 * Sheldon Fallbrook (Warner Bros. Animation (DCAU))
 * Sheldon, Missus
 * Sheldrake (Warner Bros. Animation (DCAU))
 * Shellcase
 * Shellshock (also known as Ruth Spencer)
 * Shellshock
 * Shelly
 * Shelly
 * Shelly Twopersons (also known as Michelle Twopersons)
 * Shen Hsien Pu Kwei (also known as Kwai and Nina Lam) (Milestone Media)
 * Shen Li Po
 * Shepherd (also known as Übermensch (II))
 * Shepherd, Mister (also known as Joseph Shepherd) (Vertigo)
 * Sheriff
 * Sheriff
 * Sheriff
 * Sherrif
 * Sherrif (Lippert Pictures, Inc.)
 * Sheriff Blake
 * Sheriff Guilkey
 * Sheriff Mardin
 * Sheriff of Red Gulch
 * Sheriff Todd
 * Sher-Lock (Fawcett Comics)
 * Sherlock Holmes
 * Sherman Grant (Warner Bros. Animation (DCAU))
 * Sherry Blair
 * Sheryl
 * Shiela Hanlen
 * Shield (MLJ Comics/Impact Comics)
 * Shiera Hall (also known as Hawkgirl and Hawkwoman)
 * Shiera Saunders (also known as Hawkgirl)
 * Shift
 * Shifter (Warner Bros. Animation (DCAU))
 * Shifty
 * Shifty Simpson
 * Shikari
 * Shilandra Thane
 * Shimmer
 * Shim'Tar
 * Shingo Wol (also known as Green Lantern of Space Sector 897)
 * Shining Knight (I-III) (also known as Sir Justin (I))
 * Shiny Happy Aquazon
 * Shir Kahn
 * Shirea Vaas
 * Shirley (20th Century-Fox Television)
 * Shirley Lavitsky
 * Shirley Middleman
 * Shiro Nova
 * Shiv
 * Shiva the Destroyer (DC Elseworlds)
 * Shivering Jemmy
 * Shlagen
 * Shock Trauma
 * Shockley, William
 * Shocko
 * Shockwave (also known as Arnold Pruett)
 * Shondra Kinsolving
 * Shondu
 * Shore, Mister (Vertigo)
 * Shorm
 * Short Cut
 * Short Round
 * Shorty
 * Shorty
 * Shorty
 * Shorty
 * Shorty
 * Shorty Morgan
 * Shrapnel
 * Shreck
 * Shreck, Chip (Warner Bros.)
 * Shreck, Max (Warner Bros.)
 * Shriek (also known as Walter Shreeve) (Warner Bros. Animation (DCAU))
 * Shrieve, Matthew
 * Shrike (I) & (II)
 * Shrinking Violet (also known as Yera Allon and Chameleon Girl)
 * Shugel, Gerard (also known as Ultra-Humanite)
 * Shvaughn Erin (also known as Sean Erin)
 * Shy Crazy Lolita Canary
 * Sickle
 * Sid Speed
 * Sidearm
 * Sidney
 * Sidney Debris (also known as Sid the Squid) (Warner Bros. Animation (DCAU))
 * Sidney Shelton
 * Sierra (also known as Matrix (II))
 * Sierra, Rafael
 * Sieur Satan
 * Sigmar Rhone (Vertigo)
 * Signalman
 * Signalwoman (DC Elseworlds)
 * Signstwice, Jerry
 * Silas Stone
 * Silent Knight
 * Silent Majority
 * Silent Vapor (of Judge And Jury, see Team Titans)
 * Silhouette (I)
 * Silhouette (II)
 * Silicone
 * Siliconman (Amalgam Comics)
 * Silk
 * Silk Man (Vertigo)
 * Silk Spectre (Watchmen)
 * Silken Spider
 * Silkie (also known as Larva M-319) (Warner Bros. Animation)
 * Silly Willy
 * Silver
 * Silver Banshee (also known as Siobhan McDougal)
 * Silver Cyclone (Warner Bros. Animation)
 * Silver Deer
 * Silver Fog (I-III)
 * Silver Fox
 * Silver Ghost
 * Silver Monkey
 * Silver Scarab (also known as Hector Hall and Doctor Fate)
 * Silver Shade
 * Silver Shannon
 * Silver Shield
 * Silver Slasher (also known as Ki-Lan)
 * Silver Sorceress (also known as Laura Neilsen)
 * Silver St. Cloud
 * Silver Swan (I-III)
 * Silver, Joseph (also known as Astralad)
 * Silverstone, Peter (also known as Blackrock)
 * Silversword
 * Simmons (Warner Bros. Animation (DCAU))
 * Simmons, Mister
 * Simon (Warner Bros. Animation (DCAU))
 * Simon B. Thunder
 * Simon Bennet
 * Simon Harper (Warner Bros. Animation (DCAU))
 * Simon Hurt
 * Simon LaGrieve
 * Simon Magus
 * Simon Stagg
 * Simon the Pieman (Filmation)
 * Simon Trent (also known as Gray Ghost) (Warner Bros. Animation (DCAU))
 * Simon, Carol
 * Simone (Warner Bros. Animation (DCAU))
 * Simone, Mia (Vertigo)
 * Simple Simon
 * Simpson, Iris (Amalgam Comics)
 * Simpson, Mister (Warner Bros.)
 * Simpson, Waldo (also known as Waldo the Clown)
 * Sims, Emily
 * Sims, Benjamin
 * Sims
 * Simyan
 * Sin
 * Sinbad
 * Sinclair, Andre (also known as Destroyer)
 * Sindal
 * Sindella
 * Sindra
 * Sinestro
 * Sinestro (Amalgam Comics)
 * Sinestro's father
 * Singh,David
 * Singh, Mohandas (Atari, Inc)
 * Singh, Randu
 * Sinistron (Amalgam Comics)
 * Sinkovec, Officer
 * Sinowitz, Rabbi (Milestone Media)
 * Siphon
 * Sir Deeter
 * Sir Egbert
 * Sir Norwith
 * Sir Real
 * Sir Rupert
 * Sir Swami (Warner Bros. Animation (DCAU))
 * Sireena (an alias of Talia al Ghul)
 * Siren (also known as Lorelei Circe) (20th Century-Fox Television)
 * Siren
 * Siren
 * Sirena (Filmation)
 * Sirius
 * Sirket
 * Sis
 * Siskel, Ms.
 * Sister Lilhy (also known as Lilhy)
 * Sister Mary Rose
 * Sister Rosemary
 * Sister Shadow
 * Sister Superior (also known as Vera Black and Miss Morphine)
 * Sister Wrack
 * Sisty Hunkel
 * Sivana, Beautia (Fawcett Comics)
 * Sivana, Doctor (Fawcett Comics)
 * Sivana, Georgia (Fawcett Comics)
 * Sivana, Junior (Fawcett Comics)
 * Sivana, Magnificus (Fawcett Comics)
 * Sivana, Venus
 * Sixty, Frank
 * Size Lad
 * Sizematic Twins
 * Sizemore, Kristin (WildStorm)
 * Sizzler
 * Skag
 * Skallox (also known as Red Lantern (space sector unknown))
 * Skaz (Warner Bros. Animation (DCAU))
 * Skeeter
 * Skeeter Johnson
 * Skeeter LaRue
 * Skeets
 * Skeleton
 * Skeleton Keys (Warner Bros. Animation)
 * Skeletor (Mattel)
 * Skindance
 * Skinhunter (Amalgam Comics)
 * Skinner, Buck
 * Skip Davis
 * Skip Parker (20th Century-Fox Television)
 * Skipper
 * Skipper Jones (Fawcett Comics)
 * Skippy (also known as Krypto)
 * Skirl
 * Skitch Smith
 * Skizzle Shanks (also known as Malleable Man)
 * Skoll
 * Skorpio
 * Skowcroft, Mayor
 * Skowl, Doctor
 * Skr'kl
 * Skull Biker
 * SKULL high commander
 * Skull Smasher
 * Skunch
 * Sky Pirate
 * Skyhook
 * Skylor
 * Skyman (II) (also known as Jacob Colby)
 * Skynner, Colonel
 * Sky-Raider
 * Skyrd
 * Skyrocket
 * Skyscraper
 * Slade Wilson (also known as Deathstroke and Terminator)
 * Slade, Burt
 * Slade, Jubal
 * Sladky, Carol
 * Slagg
 * Slagger
 * Slagle
 * Slam Bradley
 * Slam Bradley, Junior (also known as Smart Bomb)
 * Slapleather Smith
 * Slash (I) & (II)
 * Slash Sabre
 * Slasher (I-IV)
 * Slate, Garrison
 * Slaughter
 * Slaughter, Jonathan
 * Slaughter, Will (Vertigo)
 * Slavin, Wally
 * Slayton, Marc (also known as Backlash) (WildStorm)
 * Sledge
 * Sleepwalk (also known as Holly McKenzie)
 * Sleeves (Hanna-Barbera)
 * Sleez
 * Slicer, Doctor (Fawcett Comics)
 * Slig
 * Slim
 * Slim (Warner Bros. Animation (DCAU))
 * Slim Grimes
 * Slim Stryker
 * Slinger
 * Slingshot
 * Slinky Sam
 * Slipknot
 * Slippery B'eeef the Galactic Thief (WildStorm)
 * Slipstream
 * Slither
 * Sloan, George (also known as Off-Ramp)
 * Sloan, Hayden (Warner Bros. Animation (DCAU))
 * Sloan, Jessica
 * Sloane, Terry (also known as Mister Terrific)
 * Slob
 * Slobo
 * Slodd
 * Slug (Warner Bros. Animation)
 * Slugger
 * Slushh
 * Slyfox
 * Small, Rutherford B.
 * Smart Bomb (also known as Kellogg)
 * Smart, I.M.
 * Smashing Sportsman
 * Smatten, Jon
 * Smax
 * Smej, Major
 * Smiesel, Theodore
 * Smiling Shecky Rimshot (an alias of the Joker) (Warner Bros. Animation (DCAU))
 * Smiling Skull
 * Smirk (Warner Bros. Animation (DCAU))
 * Smith, Abdul
 * Smith, Dale (also known as Kid Empty)
 * Smith, Dale
 * Smith, Jeff
 * Smith, Jefferson (also known as Top)
 * Smith, Joe
 * Smith, Joey
 * Smith, John (also known as Red Tornado)
 * Smith, John (also known as Hawkman and Carter Hall)
 * Smith, Jonas
 * Smith, Mike
 * Smith, Mister
 * Smith, Ohiyesa (also known as Pow Wow Smith)
 * Smith, Wilma
 * Smithers, Professor
 * Smithwick (comics)
 * Smithy, Dora (Warner Bros. Animation (DCAU))
 * Smively, Jasper
 * Smoak, Felicity (also known as Felicity Smoak-Raymond)
 * Smokey Baer
 * Smolz, Bradford
 * Smoothe
 * Smyt, Mordecai
 * Smyth, Doc (also known as Smyth, Eureka)
 * Smyth, Mister
 * Smythe
 * Snafu
 * Snake Girl
 * Snap (Warner Bros. Animation (DCAU))
 * Snap Trap (also known as Sinestro Corpsman of Space Sector 3189)
 * Snapper Carr (also known as Star-Tsar and Lucas "Snapper" Carr)
 * Snapper Jones (also known as Bismuth) (Amalgam Comics)
 * Snart, Leonard (also known as Captain Cold)
 * Sneaker
 * Sneaky Danton
 * Sneed, Congressman
 * Sn'Hoj
 * Sniggle, Mister
 * Snitch
 * Snodgrass, Carlton (Fawcett Comics)
 * Snoop, Mortimer
 * Snow, Bethany
 * Snow, Elijah (WildStorm)
 * Snowflame
 * Snowman (I) & (II)
 * Snuffer
 * Snyder
 * Soames, Nancy
 * Soapy Waters
 * Sobek
 * Socialist Red Guardsman
 * Socko Strong
 * Socrates, Horatio (also known as Mister Socrates and Robert Barton)
 * Sodam Yat (also known as Ion)
 * Sodium
 * Sodom
 * Sofia Arkadin
 * Sofia Constantinas
 * Soft-Shoe Sapper
 * Sol, Chuckie (Warner Bros. Animation (DCAU))
 * Sol Simon
 * Solaar
 * Solar Brain
 * Solar Sentinel
 * Solar, Mister
 * Solaris, the Tyrant Sun
 * Soldier (also known as (possibly) Scout)
 * Soliony
 * Soljer (also known as Essad)
 * Sollis (see Lightray)
 * Solomon (Fawcett Comics)
 * Solomon Wayne
 * Solomon Grundy
 * Solomon, King (America's Best Comics)
 * Solovar
 * Solution
 * Somers, Ed
 * Somi Gan (also known as Life Lass)
 * Sommerly, Cissie (Fawcett Comics)
 * Sommers, Michael (also known as Alpha)
 * Somnambulist (DC Elseworlds)
 * Son of the Joker
 * Son of Vulcan
 * Sonar (I) & (II)
 * Songbird
 * Sonia Alcana (also known as Batwoman) (Warner Bros. Animation (DCAU))
 * Sonik (also known as Vicky Grant)
 * Sonja
 * Sonny Apollo
 * Sonny Chibwa
 * Sonny Sumo
 * Sonya
 * Sonya Chuikov (also known as Fireball (II))
 * Sonya Sophia
 * Sonya Vatkoff
 * Sool
 * Sooner
 * Soong, Kevin (also known as Survivor)
 * Soozie-Q (also known as 500Z-Q)
 * Sophie Edelstein
 * Soranik Natu
 * Soraya Nassur
 * Sorban
 * Sorcerer's World Teacher (Air)
 * Sorcerer's World Teacher (Earth)
 * Sorcerer's World Teacher (Fire)
 * Sorcerer's World Teacher (Light)
 * Sorcerer's World Teacher (Water)
 * Sorceress (Mattel)
 * Sorensen, Karel
 * Sorrow, Johnny
 * Soullet, Gabrielle (an alias of Madame Rouge)
 * Soullet, Gabrielle
 * Soullet, Professor
 * Source
 * Source (Warner Bros. Animation)
 * Southpaw
 * Southside Eddie (Warner Bros. Animation (DCAU))
 * Space Cabbie (also known as Space Cabby)
 * Space Ghost (Hanna-Barbera)
 * Space Looter
 * Space Marshall
 * Space Ranger
 * Spaceman
 * Spade (DC Elseworlds)
 * Spade, Jack (also known as Hijack)
 * Spaghetti, J. Pauline (20th Century-Fox Television)
 * Spain (Vertigo)
 * Spak-Drom
 * Span, Flodo
 * Spark (also known as Ayla Ranzz)
 * Sparkler
 * Sparks Barron
 * Sparks, Gary
 * Sparks, Jenny (WildStorm)
 * Sparky
 * Sparky
 * Sparky (also known as Sparkington J. Northrup) (Fox Feature Syndicate)
 * Sparky Hahn
 * Sparrow (also known as Jubilation Lee) (Amalgam Comics)
 * Sparrow, Elizabeth
 * Sparta of Synriannaq
 * Spartan (also known as Hadrian) (WildStorm)
 * Sparx
 * Spaulding, Roxanne (also known as Freefall) (WildStorm)
 * Spaulding, Tom
 * Spawn of Frankenstein (also known as Frankenstein Monster)
 * Spazz
 * Special Agent Porter (Warner Bros. Animation)
 * Special Prosecutor Maloney (also known as District Attorney Maloney)
 * Spectarns
 * Spectre (I-V) (also known as Aztar, Jim Corrigan, Hal Jordan and Crispus Allen)
 * Spectrumonster
 * Speed
 * Speed Demon (also known as Jerry McGee)
 * Speed Demon (also known as Jay Garrick and Etrigan the Demon) (Amalgam Comics)
 * Speed Demon (also known as Blaze Allen and Etrigan) (Amalgam Comics)
 * Speed Force
 * Speed Queen
 * Speed Saunders (also known as Cyril Saunders)
 * Speed Saunder's ex-wife
 * Speedy (I) & II (Speedy (I) now Arsenal)
 * Speer, Laszlo
 * Spellbinder (I) & (II)
 * Spellbinder (also known as Ira Billings) (Warner Bros. Animation (DCAU))
 * Spellcraft, Cassandra (20th Century-Fox Television)
 * Spence, Jonathan
 * Spence, Horten
 * Spencer, Alice (also known as Alice White)
 * Spencer, Ian
 * Spencer, Judge
 * Spencer, Kathy
 * Spender, Paul
 * Spera
 * Spera Zombi
 * Spice (Warner Bros.)
 * Spider
 * Spider (Quality Comics)
 * Spider (WildStorm)
 * Spider Conway (Warner Bros. Animation (DCAU))
 * Spider Girl (also known as Sussa Pakk)
 * Spider Jerusalem
 * Spider Lady (Columbia Pictures)
 * Spider Widow
 * Spider-Boy (also known as Pete Ross) (Amalgam Comics)
 * Spiezel, Hiram
 * Spike
 * Spike
 * Spike (Fawcett Comics)
 * Spike (Warner Bros. Animation (DCAU))
 * Spike Wilson
 * Spike Yaeger
 * Spin Doctor (I) & (II)
 * Spindly Klutz (Hostess)
 * Spinner (Warner Bros. Animation)
 * Spinner, Dorothy
 * Spiral
 * Spirit King
 * Spiro
 * Spitfire
 * Spitting Cobra
 * Splash Brannigan (America's Best Comics)
 * Split
 * Splitshot (of Superior Five)
 * Spoiler
 * Spol
 * Spook
 * Spore
 * Sportsman
 * Sportsmaster (I) & (II)
 * Springer, Werner
 * Spruance, Admiral
 * Spruce, Lucius (also known as Hobby Napper)
 * Spunky Spencer (Warner Bros. Animation (DCAU))
 * Sputnik, Zoot
 * Spot
 * Spy Smasher (also known as Alan Armstrong) (Fawcett Comics)
 * Spy Smasher (also known as Katarina Armstrong)
 * Spyder
 * Squagga
 * Square Deele
 * Squid (also known as Lawrence Loman)
 * Squire (I-III)
 * Squire, Raymond (DC Comics/''Dark Horse Comics')
 * Squawky the Super-Parrot
 * Sqweeegg
 * SR-12
 * Srang
 * Stacked Canary
 * Stacy
 * Stacy
 * Stacy Conwell
 * Stacy Darnell
 * Stacy Taglia (also known as Zip-Kid)
 * Stacy, Professor
 * Stacy's boyfriend
 * Stagg, Randall
 * Stalin, Joseph
 * Stalker
 * Stalker (Warner Bros. Animation DCAU))
 * Stalker (WildStorm)
 * Stallion
 * Stalnoivolk
 * Stan
 * Stan
 * Stan
 * Stan Kitch
 * Stan Doborak
 * Stan Lynch (also known as Barricade) (Hasbro)
 * Stan Merkel (also known as Officer Merkel)
 * Stan Rivers
 * Stan Walker
 * Stan Wellwood
 * Stanch
 * Standing, John
 * Standler, Buddy (also known as Condiment King) (Warner Bros. Animation (DCAU))
 * Stanislaus (Quality Comics)
 * Stanislaus Johns
 * Stanislaw Kober
 * Stanley
 * Stanley Dover
 * Stanley Hale
 * Stanley Labowski (also known as Mad Stan) (Warner Bros. Animation (DCAU))
 * Stanley Stark
 * Stanley "Stinky" Printwhistle (also known as Ibac) (Fawcett Comics)
 * Stanton
 * Stanton Vreeland (Warner Bros. Animation (DCAU))
 * Stanton Vreeland (Warner Bros. Animation (DCAU))
 * Stanton, Doctor (Warner Bros. Animation (DCAU))
 * Stanton, Jeff
 * Stanton, Kenny (also known as Payback) (Warner Bros. Animation (DCAU))
 * Staq Mavlen (also known as Fire Lad)
 * Star Bolt (DC Elseworlds)
 * Star Boy (also known as Thom Kallor, Starman and Sir Prize)
 * Star Hawkins
 * Star Sapphire (I-IV) (also known as Carol Ferris (Star Sapphire (II)))
 * Starbreaker
 * Starfinger (also known as Lars Hanscom(b))
 * Starfinger (also known as Lightning Lad)
 * Starfinger (also known as Char Burrane)
 * Starfinger (also known as Molock Hanscom)
 * Starfire (I-II) (also known as Red Star)
 * Starfire (III)
 * Starfire (IV) (also known as Koriand'r)
 * Stargirl (also known as Star-Spangled Kid, Courtney Whitmore and Starwoman)
 * Stargrave (also known as Pulsar Stargrave and Brainiac)
 * Starheart
 * Stark, Hal (also known as Iron Lantern) (''Amalgam Comics')
 * Stark, Hugo
 * Stark, Jack (also known as Terror)
 * Stark, Mister
 * Starkey, Vincent (Warner Bros. Animation (also known as Shark) (DCAU))
 * Starkaor (also known as Green Lantern of Space Sector 2814)
 * Starlight (also known as Natasha Irons)
 * Starling
 * Starman (also known as Ted Knight)
 * Starman (also known as Jack Knight)
 * Starman (also known as Will Payton)
 * Starman (also known as Mikaal Tomas)
 * Starman (also known as Prince Gavyn)
 * Starman (also known as David Knight)
 * Starman (also known as Thom Kallor and Danny Blaine)
 * Starman (also known as Farris Knight)
 * Starman (also known as Victor Sono)
 * Starman (an alias of Doctor Mid-Nite (Charles McNider))
 * Starman (an alias of Batman (Bruce Wayne))
 * Star-Man
 * Starr, Bronco Billy (also known as Comet)
 * Starr, Karen (also known as Power Girl (II), Kara of Atlantis, Nightwing (VIII) and Power Woman (DC Elseworlds))
 * Starr, Professor
 * Starra (Quality Comics)
 * Starro (I)
 * Starro (II)
 * Stars (DC Elseworlds)
 * Starshine
 * Starshrike
 * Star-Spangled Kid (III) (also known as Miss Martian)
 * Star-Tsar (also known as Snapper Carr; also known as The Key; also known as Manhunter/Privateer/Mark Shaw)
 * Star-Tsar (also known as Richard Rigel)
 * Stash (Warner Bros. Animation (DCAU))
 * Stasis
 * Static (see also Static Shock) (Milestone Media)
 * Stavros Christadoulodou
 * Stavros, Yanni (Warner Bros. Animation (DCAU)
 * St'balla
 * Stealth
 * Stealth (Earth-22) (DC Elseworlds)
 * Steamboat (Fawcett Comics)
 * Steamroller
 * Steamroller (Warner Bros. Animation)
 * Steel (I) & (II)
 * Steel (III) (John Henry Irons)
 * Steel (IV) (also known as Natasha Irons)
 * Steel Claw (WildStorm)
 * Steel Hawk
 * Steel, John Henry (also known as Iron) (Amalgam Comics)
 * Steel Sterling (MLJ Comics/Impact Comics)
 * Steelclaw
 * Steele Kerrigan
 * Steele, Cliff (also known as Robotman)
 * Steelhand
 * Steeljacket
 * Steeplechase, Bianca (DC Elseworlds)
 * Stefan Wasserman (Vertigo)
 * Stefanacci, Antonio
 * Steffens, Doctor
 * Stegler, Marvin (Vertigo)
 * Steicher, Helmut (also known as Red Panzer)
 * Stein, Harry (also known as King (I))
 * Stein, Martin (also known as Firestorm)
 * Steiner, Professor (Quality Comics)
 * Stel (also known as Green Lantern of Space Sector 3009)
 * Stella Bates (Warner Bros. Animation (DCAU))
 * Stellara
 * Stephanie Edge
 * Stephanie Lake (Warner Bros. Animation (DCAU))
 * Stephen
 * Stephen Davis (Warner Bros. Animation (DCAU))
 * Stephens, Gerard (Warner Bros.)
 * Stepnik, Adam (Warner Bros. Animation (DCAU))
 * Steppe
 * Steppenwolf
 * Sterling Morris (Fawcett Comics)
 * Sterling Silversmith
 * Sterling, Donald
 * Sterling, Elaine
 * Sterling, Rand
 * Stern (Warner Bros. Animation (DCAU))
 * Stern, Franklin
 * Stern, R. Lowell
 * Steve
 * Steve
 * Steve (DC Comics/''Dark Horse Comics')
 * Steve Allen
 * Steve Bevan
 * Steve Billman
 * Steve Carter
 * Steve Dale
 * Steve Frank
 * Steve Grant
 * Steve Lombard
 * Steve London
 * Steve Power
 * Steve Trevor
 * Steven Carlyle (Warner Bros. Animation (DCAU))
 * Steven Carlyle (plant clone) (Warner Bros. Animation (DCAU))
 * Steven Crane
 * Steven Tetsuo (Warner Bros. Animation (DCAU))
 * Stevens, Dave
 * Stevie Trevor (also known as Wonder Girl, Stephanie Trevor and Wonder Woman II) (DC Elseworlds)
 * Stewart Grean
 * Stewart Lowe (also known as 2-D Man) (Warner Bros. Animation (DCAU))
 * Stewart, Eric
 * Stewart, Jane
 * Stewart, John (also known as Green Lantern)
 * Stewart, Paul
 * Stewart, Rex (also known as Warhawk) (DCAU)
 * Stewart, Troy (also known as Tyroc)
 * Stewirt, Klint (also known as Golden Boy)
 * Stheno
 * Strickley, Fred (Warner Bros.)
 * Sticky-Mitt Stimson
 * Stilwell, Joseph
 * Sting
 * Stinger
 * Stinky
 * Stirk, Cornelius
 * Sti-Tuan, Yer (also known as Silver Slasher)
 * Stix
 * St'nlli
 * Stockton, Matt
 * Stoker, Congressman
 * Stokis, Missus (Warner Bros.)
 * Stokis, Mister (Warner Bros.)
 * Stom, Prime Minister
 * Stompa
 * Stone (also known as Cyborg)
 * Stone Boy (also known as Dag Wentim)
 * Stone, Dan (also known as Flow and Glob (II))
 * Stone, Elias (also known as Midnight Rider)
 * Stone, Drew (Warner Bros. Animation (DCAU))
 * Stone, Elinore
 * Stone, Frederick
 * Stone, John (WildStorm)
 * Stone, Vic (also known as Cyborg)
 * Stonefeller, Governor (20th Century-Fox Television)
 * Stoneman
 * Stoney Croy
 * Stonk
 * St'onon
 * Storm Boy (also known as Myke Chypurz)
 * Storm, Axel (also known as Brain Storm)
 * Storm, Captain (also known as William Storm)
 * Storm, Donna
 * Storm, Fred (also known as Brain Storm)
 * Storm, Johnny (also known as Red Storm) (Amalgam Comics)
 * Storme, Captain
 * Storme, Zeb
 * Storm-God
 * Storms, Brain
 * Stormtrooper, Johnny (also known as Jonathan Stormtrooper) (Amalgam Comics)
 * Storn, Erik (also known as Fury)
 * Storski, Bull
 * Stradivous (Quality Comics)
 * Strafe (also known as Bellerophon and Malcolm King) (WildStorm)
 * Strang, Yale
 * Strange Visitor
 * Strange, Adam
 * Strange, Alanna
 * Strange, Aleea (also Kingdom Come (DC Elseworlds))
 * Strange, Hugo
 * Strangeglove, Doctor
 * Stranglehold
 * Strata
 * Stratos (WildStorm)
 * Straussman, Nathan
 * Streak (Warner Bros. Animation (DCAU))
 * Streak the Wonder Dog
 * Streaky
 * Street (WildStorm)
 * Strega
 * Streicher, Helmut (also known as Red Panzer)
 * Strel (Vertigo)
 * Strenstrom
 * Stretch
 * Striker Z
 * Stripes (DC Elseworlds)
 * Strobe (also known as Edg the Destroyer)
 * Stroh, Rori
 * Stromer, Rod
 * Stromwell, Arnold (Warner Bros. Animation (DCAU))
 * Stromwell, Connie (Warner Bros. Animation (DCAU))
 * Stromwell, Joey (Warner Bros. Animation (DCAU))
 * Stromwell, Michael (Warner Bros. Animation (DCAU))
 * Strong Bow
 * Strong Girl
 * Strong, Captain (also known as Horatio Strong)
 * Strong, Tom (America's Best Comics)
 * Strongman
 * Strontium
 * Stryker
 * Stryker, Alfred
 * Stryker, Fred
 * Stryker, Priscilla (also known as Pesticide)
 * Stu Solomon
 * Stuart Campbell (also known as White Knight) (Warner Bros. Television)
 * Stuart Pemberton
 * Stuart, Betty
 * Stuart, Jeb (I)
 * Stuart, Jeb (II) (also known as Jeb Stuart (II)) (also known as Jeb Stuart Smith)
 * Stuff the Chinatown Kid (I) & (II)
 * Stumpy
 * Stuporman (Quality Comics)
 * Sturmer
 * Stylist
 * Styren
 * Suarez, Fernando (also known as Whip and El Castigo)
 * Subaltern Jones
 * Subject 044 (WildStorm)
 * Sublime
 * Sudbury, Buford
 * Sudden Death
 * Sude (also known as Supreme Decider)
 * Sue
 * Sue Denim
 * Sue Dibny
 * Sue Johnston
 * Sue-Ellen (It's a Bird...It's a Plane...It's Superman)
 * Sue Storm (also known as Ace Storm) (Amalgam Comics)
 * Sugar (Warner Bros.)
 * Sugar Plumm
 * Sugar Puss
 * Sugarman, Doctor (Milestone Media)
 * Sugyn
 * Suit
 * Su-Lehmon
 * Suleiman Yogul
 * Sul-El
 * Suli
 * Sullivan (Tribune Media Services)
 * Sullivan, Francis (also known as Made of Wood Killer)
 * Sullivan, Isobel
 * Sumaan Harjavti
 * Summer Gleeson (Warner Bros. Animation (DCAU))
 * Summer, Bobbi "Blade" (Warner Bros. Animation (DCAU))
 * Summers, Ray (also known as Apollo) (Amalgam Comics)
 * Sumo the Samurai
 * Sun Boy (also known as Dirk Morgna)
 * Sun Emperor
 * Sun Girl
 * Sun King
 * Sun Woman
 * Sun Woman (also known as Delia Spyros) (America's Best Comics)
 * Sunbeam, Cecil
 * Sunburst
 * Sunburst
 * Sunburst (also known as Karl Hansen) (WildStorm)
 * Sundae Supplement
 * Sundeath
 * Sunder, Doctor
 * Sundown (also known as Walker Calhoun) (Hasbro)
 * Sun-Eater
 * Sunny
 * Sunspotter
 * Super Dood (also known as Bibbo Bibbowski)
 * Super Moby Dick
 * Super Nova (also known as Robby Reed)
 * Super-Ape
 * Super-Baby
 * Superbo
 * Superboy (also known as Clark Kent and Kal-El)
 * Superboy (also known as Kal-El and Clark Kent) (pocket universe)
 * Superboy (also known as Kon-El and Conner Kent)
 * Superboy
 * Superboy 820
 * Superboy 3541
 * Superboy Robot (also known as Alpha-Domino-5)
 * Superboy-Prime
 * Super-Caesar (also known as Rufus Caesar)
 * Super-Chief (I) & (II)
 * Supergirl (also known as Kara Zor-El, Linda Lee Danvers, Flamebird (V), Claire Connors, Linda Lang and Satan Girl)
 * Supergirl (II-V)
 * Supergirl (also known as Kara Kent) (Warner Bros. Television),
 * Supergirl (also known as Kara In-Ze) (Warner Bros. Animation (DCAU))
 * Super-Girl
 * Supergirl android
 * Supergirl Blue (also known as Lara Wayne) (DC Elseworlds)
 * Supergirl Red (DC Elseworlds)
 * Super-Hip
 * Superintendent Martin
 * Superintendent Wyman
 * Superlad
 * Superman (also known as Kal-El, Clark Kent, Superman-T/Superman-X and Superman Red/Superman Blue)
 * Superman (also known as Kal-L and Clark Kent)
 * Superman (alternate Earth version I)
 * Superman (alternate Earth version II)
 * Superman (also known as Kal-El and Bruce Wayne)
 * Superman (clone)
 * Superman, Junior (also known as Johnny Kirk)
 * Superman, Junior (also known as Clark Kent, Junior)
 * Superman II (also known as Jor-El II)
 * Superman-II (also known as Jorel Kent)
 * Superman-III (also known as Kalel Kent)
 * Super-Menace (also known as Clark Kent (duplicate), Kal-El (duplicate), Super-Brat and Super-Bully)
 * Super-Moby Dick
 * Superman Monster
 * Superman of 2956 (also known as Craig King)
 * Superman of 2965 (also known as Klar Ken T5477)
 * Superman Robot Z
 * Superman the 4th
 * Superman the 5th
 * Superman the 7th (also known as Kanton K-73)
 * Supernova
 * Super-Sister (also known as Claire Kent)
 * Super-Soldier (Amalgam Comics)
 * Super-Squirrel
 * Super-Turtle
 * Superwoman (I-III)
 * Superwoman Robot
 * Super-X
 * Supplier
 * Supreme Chairman of Qward (Warner Bros. Animation)
 * Supreme One
 * Sur, Abin
 * Sur, Amon
 * Sur, Arin
 * Sur, Rhomann (Amalgam Comics)
 * Sure-Shot (also known as Mister Weapon, the Living Arsenal)
 * Surgeon (WildStorm)
 * Surley, Frank
 * Surrillo, Janet (Warner Bros.)
 * Surya
 * Susan Barr (also known as Bulletgirl) (Fawcett Comics)
 * Susan Maguire (also known as Susan Wayne) (Warner Bros. Animation (DCAU))
 * Susan Meadows
 * Susan Palmer (also known as Mary Palmer)
 * Susan Stanyon
 * Susanna Shakespeare (Vertigo)
 * Susano-o-no-Mikoto
 * Susanna Chaste (WildStorm)
 * Susie
 * Susie Tompkins
 * Suspect #1 (It's a Bird...It's a Plane...It's Superman)
 * Suspect #2 (It's a Bird...It's a Plane...It's Superman)
 * Suspect #3 (It's a Bird...It's a Plane...It's Superman)
 * Suspect #4 (It's a Bird...It's a Plane...It's Superman)
 * Suspect #5 (It's a Bird...It's a Plane...It's Superman)
 * Sutcliffe, Walter
 * Sutton, Kathy
 * Sutton, Roxanne (also known as Roxy Rocket) (DCAU)
 * Sutton, Traya
 * Suzette Ledbetter (also known as Rush (I)) (WildStorm)
 * Suzie Jamie Donatello
 * Suzuki, Doctor (also known as Repeller) (Warner Bros. Animation (DCAU))
 * Svensen, Ingrid
 * Swab Decker (Quality Comics)
 * Swamp Thing (also known as Alec Holland)
 * Swamp Thing (also known as Alec Holland) (Embassy Pictures)
 * Swan, Chris
 * Swan, Curt
 * Swashbuckler (also known as Michael Carter)
 * Swashbuckler (an alias of Green Arrow)
 * Swastika (DC Elseworlds)
 * Sweeney
 * Sweep Second (also known as Thorndyke Thompkins)
 * Sweet 16
 * Sweet Tooth (Filmation)
 * Sweet Tooth (Vertigo)
 * Swift (also known as Shen Li-Min) (WildStorm)
 * Swing Sisson (Quality Comics)
 * Swirski, Officer (Vertigo)
 * Swordini the Slasher
 * Swordo (Quality Comics)
 * Sybil
 * Sybil Haden
 * Sydney Happersen (also known as Doctor Sydney Happersen)
 * Sydney Sharp (It's a Bird...It's a Plane...It's Superman)
 * Sykes
 * Sykes, Ike
 * Sykes, Mike
 * Mister Sykes (52/World War III Part Three: Hell Is for Heroes)
 * Sykes, Ruthven (Vertigo)
 * Sylph
 * Sylvester Pemberton (also known as Star-Spangled Kid and Skyman (I))
 * Sylvia Feltman
 * Sylvian, Philip
 * Symbioship
 * Symon Terrynce
 * Synaptic Kid
 * Synce, Doctor
 * Synergy (WildStorm)
 * Synn, Onimar (also known as Sin-Eater)
 * Synnar the Demiurge
 * Syonide (I) & (II)
 * Syrene
 * Sythe, Noam